MSC Cruises has cancelled the full winter program of the MSC Orchestra that was planned in the Red Sea from November through April because of the proximity of some of ship’s ports of call to Israel and the number of restrictions in the bordering countries that would have adversely affected the holiday experience for passengers, the company said in a statement released Monday morning.

The winter program for the MSC Sinfonia from has also been cancelled as the ship’s main highlight in its itinerary was Haifa in Israel, MSC said in its statement.

The line is also making changes to some of its other itineraries in light of the current geopolitical situation and to ensure the safety of its passengers and crew.

MSC said that some travel restrictions have been made by local authorities in certain destinations and also some national governments have issued advisories against travel to certain areas.

In addition are minor changes to the itineraries of the grand voyages for MSC Virtuosa, MSC Opera and MSC Splendida and to two 11-night sailings for MSC Armonia.

Passengers affected by the changes can move their cruise of a similar length of travel to an alternative ship and itinerary or request a full refund.

MSC said added that the safety of its passengers and crew is always its upmost priority and during an evolving situation it will continue to monitor the situation and modify ship itineraries if necessary.